Background: Arteriovenous fistulae (AVF) are the hemodialysis access modality of choice for patients with endstage\nrenal disease. However, they have a high early failure rate. Good vascular access is essential to manage longterm\nhemodialytic treatment, but some anesthesia techniques directly affect venous diameter as well as intra- and\npost-operative blood flow. The main purpose of this meta-analysis was to compare the results of regional and local\nanesthesia (RA and LA) for arteriovenous fistula creation in end-stage renal disease.\nMethods: We conducted a systematic review and meta-analysis to synthesize evidence from 7 randomized\ncontrolled trials (565 patients) and 1 observational study (408 patients) with the aim of evaluating the safety and\nefficacy of RA versus LA in surgical construction of AVF.\nResults: Pooled data showed that RA was associated with higher primary patency rates than LA (odds ratio [OR],\n1.88; 95% confidence interval....................
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